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Symbol
Name
ID
E2f4
E2F transcription factor 4
MGI:103012
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Gastrointestinal hemorrhage
Hematological neoplasm
Disease(s) Associated with E2F4
Lynch syndrome

Mouse Phenotypes
thymus hypoplasia
decreased thymocyte number
abnormal definitive hematopoiesis
abnormal stress erythropoiesis
increased double-negative T cell number
decreased double-positive T cell number
anemia
abnormal proerythroblast morphology
decreased erythrocyte cell number
decreased hematocrit
increased nucleated erythrocyte cell number
anisocytosis
increased number of Howell-Jolly bodies
macrocytosis
abnormal granulocyte morphology
decreased granulocyte number
increased NK cell number
reticulocytosis
abnormal reticulocyte morphology
Availability Mouse Genotype
E2f4tm1Jrn/E2f4tm1Jrn
E2f4tm1Lees/E2f4tm1Lees

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory